NO
On $50,000/yr, the typical $335,357 home in Columbus, OH needs $100,749/yr ($2,351/mo). Your gap: $-50,749 — housing would be 56.4% of your gross income.
The math
335,357 price − 10% down (33,536) = 301,821 loan
30-yr fixed at 6.69% on 301,821 = 1,946/mo principal+interest
+ 405/mo est. taxes+insurance (1.45%/yr of value — national placeholder)
2,351/mo PITI ÷ 0.28 = 8,396/mo → 100,749/yr required
against Zillow ZHVI 2026-06 and the 6.69% FRED 30-yr rate (2026-08-06).
What salary WOULD clear Columbus, OH?
You need about $100,749/yr for the typical home. That's $50,749 more than $50,000.