NO
On $50,000/yr, the typical $333,537 home in Columbus, OH needs $98,334/yr ($2,294/mo). Your gap: $-48,334 — housing would be 55.1% of your gross income.
The math
333,537 price − 10% down (33,354) = 300,183 loan
30-yr fixed at 6.47% on 300,183 = 1,891/mo principal+interest
+ 403/mo est. taxes+insurance (1.45%/yr of value — national placeholder)
2,294/mo PITI ÷ 0.28 = 8,195/mo → 98,334/yr required
against Zillow ZHVI 2026-05 and the 6.47% FRED 30-yr rate (2026-06-18).
What salary WOULD clear Columbus, OH?
You need about $98,334/yr for the typical home. That's $48,334 more than $50,000.